Lineage-22.2-20250414-NIGHTLY-pro1x with April 1st security patch installed smoothly via OTA. MindTheGapps15, and root was maintained.
Notes: I encountered no problems after the OTA going from 22.1 to 22.2. I use Magisk, but only as SU, I don't use any Magisk modules.
Also, since I update OTA, I don't flash newer packages of MindTheGapps. My contention is, that since Google updates both the Gapps and Play services, there is no need to flash the newer MTG packages unless you are moving to a new full version of Lineage (new version of Android) that can't be installed OTA. I don't k