I use my Pro1 as daily driver with my self-built LineageOS 16.0 and a Debian 10 (actually Devuan 3) desktop GNU/Linux system running permanently in a chroot. For me this is the optimal combination of an Android(-like) environment with the option to do serious (desktop) work from the GNU chroot.
Of course, running a more native GNU/Linux system (if we agree on calling libhybris-based hacks "native" 😉 ) like UbuntuTouch, Sailfish, or Droidian is tempting, but -- realistically -- I cannot make it through the day without some Android apps I would not know how to replace (Firefox, Zoom, Öffi,